Name: Italian Butternut Squash and Spinach Lasagna
Prep time: 30 min
Cook time: 1 h
Total time: 1 h 30 min
Cuisine: Italian
Ingredients: 1 medium butternut squash, peeled and cubed; 2 tablespoons olive oil; Salt and pepper, to taste; 1 tablespoon butter; 2 cloves garlic, minced; 1 onion, finely chopped; 1 (10 oz) bag fresh spinach; 1/4 teaspoon ground nutmeg; 1/4 teaspoon red pepper flakes (optional); 3 tablespoons butter (for béchamel); 3 tablespoons all-purpose flour (for béchamel); 2 1/2 cups milk (for béchamel); 1/4 teaspoon salt (for béchamel); 1/4 teaspoon ground black pepper (for béchamel); 1/4 teaspoon nutmeg (for béchamel); 9 lasagna noodles, cooked and drained; 1 1/2 cups shredded mozzarella cheese; 1/2 cup grated Parmesan cheese

Why You’ll Love Italian Butternut Squash and Spinach Lasagna Recipe

This butternut squash and spinach lasagna reinvents a traditional favorite with nutritious veggies and a creamy texture. The naturally sweet squash pairs beautifully with savory cheeses and spinach, creating layers of flavor without heavy red sauce. It’s also versatile, make-ahead friendly, and can easily be adapted to gluten-free or dairy-free diets.

Ingredients

(Tip: You’ll find the full list of ingredients and measurements in the recipe card below.)

For the butternut squash mixture:
butternut squash puree
ricotta cheese
milk
salt
nutmeg

For the spinach layer:
fresh spinach
ricotta cheese
shredded mozzarella cheese
garlic cloves
salt
black pepper

For layering and topping:
lasagna noodles
shredded mozzarella cheese
grated parmesan cheese
Italian seasoning
paprika
dried basil

Directions

Prepare the butternut squash mixture by combining mashed squash with ricotta, milk, salt, and nutmeg until smooth and creamy.
In a mixing bowl, combine cooked and drained spinach with ricotta, shredded mozzarella, garlic, salt, and black pepper. Mix well.
Cook the lasagna noodles in boiling water until al dente, then drain and rinse under cold water.
Preheat the oven and lightly grease a baking dish. Spread a layer of butternut squash mixture on the bottom. Add a layer of noodles, then spinach mixture, and repeat the layers.
Finish with a final layer of squash mixture, top with mozzarella and parmesan, and sprinkle with Italian seasoning, paprika, and dried basil.
Cover with foil and bake until heated through, then uncover to brown the cheese. Allow the lasagna to rest before slicing.

Servings and timing

Serves approximately 4 to 6 people. Prep time is about 30–45 minutes and baking time is around 40–50 minutes. Total time including resting is roughly 75–95 minutes.

Storage/Reheating

Refrigerate any leftovers tightly covered for up to 4 days. To reheat, warm individual portions in the microwave or cover with foil and bake in the oven until heated through. This lasagna also freezes well—wrap it securely and freeze for up to 3 months; thaw before baking and add extra bake time if still cold.

FAQs

What type of squash is best for this lasagna?

Fresh butternut squash with firm skin and a heavy feel is ideal, though pre-made squash puree works well too.

Can I use frozen spinach instead of fresh?

Yes, just thaw and squeeze out all excess water before mixing.

Is there a gluten-free option?

Gluten-free lasagna noodles can be substituted easily.

Can this lasagna be made ahead of time?

Yes, it can be assembled a day ahead and baked when ready.

How do I prevent a watery lasagna?

Ensure squash puree and spinach are well drained before layering.

Can I use a different cheese?

Provolone or fontina can be swapped for mozzarella; part-skim options reduce richness.

What can I serve with this lasagna?

A crisp green salad or garlic bread balances the creamy richness well.

Can I double the recipe?

Yes, you can double ingredients for a larger dish, adjusting bake time as needed.

How do I reheat leftovers without drying them out?

Cover with foil and add a splash of milk or water around edges before reheating.

Can I freeze the lasagna before baking?

Yes, freezing unbaked lasagna works; add extra bake time when cooking from frozen.

Conclusion

This Italian butternut squash and spinach lasagna is a flavorful, comforting dish that brings a fresh twist to traditional lasagna. With rich, creamy layers of squash, spinach, and cheese, it’s a satisfying vegetarian centerpiece perfect for family dinners and gatherings. Its versatility—whether made ahead, adapted for dietary needs, or frozen for later—makes it a reliable recipe to return to again and again.